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School of Biological Sciences School of Biological Sciences

UC San Diego's School of Biological Sciences Newsletter

Scientists Unveil Surprising Human vs Mouse Differences in Major Cancer Immunotherapy Target

Much of our knowledge of the protein PD-1, a leading cancer treatment target, comes from studies in mice. In a comprehensive assessment, researchers have found that PD-1 in mice is significantly weaker than the human version, providing new information on how cancer treatments are developed.